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EU - FP 6: IMMUNANOMAP - Unravelling the nano-landscape of receptors controlling molecular processes of the immune system
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PROJEKT: The major objective of IMMUNANOMAP is to rain the next generation of multidisciplinary researchers to operate at the intersections of nano-technology, nano-chemistry, molecular cell biology and immunology.
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Interdisciplinary researchers are needed to develop tools and insights into our molecular understanding of the cell as a central entity of all living organisms and unravel the mechanisms underlying the defence against pathogens. Novel microscopic techniques now provide the tools to cell biologists and immunologists to study cellular processes at the nanometre and single molecule scale.
Particularly in the immune system, which defends our body against pathogens, the recognition and elimination of nanometre-sized pathogens is regulated through complex cell signalling to ensure a swift and effective protective response. How these cell surface processes are orchestrated is poorly understood. For the first time, the technology is within reach to unravel the nano-landscape of surface receptors of cells of the immune system and get dynamic information of their organization and subsequent signalling pathways at the nano-metre level.
We hope to reach out goal by:
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| Thorough multidisciplinary training both at the theoretical and practical level to a truly interdisciplinary field of young and experienced researchers consisting of physicists, surface chemists, cell biologists and immunologists, and
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| exploiting state-of-the-art imaging techniques to understand the molecular organization of cell surface and signalling pro cesses pertinent to the functioning of the immune system.
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Thus we anticipate eliminating a major limitation in multidisciplinary work that restricts scientific and economic progress due to fundamental differences in the background of scientists in these diverse disciplines. To achieve this, 7 renowned research institutes and 1 SME, each specialized in different aspects of bio-nanotechnology, join forces in this European research and training collaboration.
Source: CORDIS, http://cordis.europa.eu
Project details
Funding period: 01.03.2007 - 28.02.2011
Participant organisations: 7
Project funding: 2.960.000 Euro
Web www.immunanomap.eu
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